Yagya (agni-Yagya) is not only an excellent process of environmental purification, but it could also be used as a powerful remedy against varieties of physical (bodily) and psychiatric diseases and psychosomatic disorders by proper selection of wood and havan-s³magri. Appropriate selection of mantras and mode and timings of Yagya etc promise outstanding applications for total health. Gurudev Pt. Shriram Sharma Acharya, the spiritual scientist and rishi of our times, had pioneered reinvestigating this lost science in the modern laboratories. He had named this Yagya-based universal therapy for total health as “yagyopathy” and established specialized laboratories at Brahm Varchas Research Center of Shantikunj, Hardwar for this farsighted purpose. He also inspired and engaged medical doctors and talents from different disciplines of biological, physicochemical and psychological sciences in this path-breaking research.